Dr. Christopher J. Cordier
Dr. Christopher J. Cordier

Dr. Christopher J. Cordier

Head of Chemistry Research, GROW® Biotech

Name

Dr. Christopher J. Cordier

Background

Dr Cordier’s research experience spans Pharmacology, Biochemistry, Chemical Biology, Organic Chemistry, Total Synthesis, and Stereoselective Catalysis. Following completion of his PhD, he conducted postdoctoral research at the University of Cambridge, Massachusetts Institute of Technology, and California Institute of Technology. Dr Cordier accepted a Royal Society University Research Fellowship and began his independent academic career at Imperial College London and the pioneering opportunities in the growing cannabis research and medical space attracted him to GROW 2018.

Motivation

“I’ve often felt that the biggest challenge for scientists is selecting the most impactful areas for investigation. Research into the therapeutic applications of cannabis-based medicinal products (CBMP) has been hampered by legislative barriers put in place due to concerns regarding misuse. As public and regulatory perceptions of cannabis have evolved, exciting new opportunities have been presented within the technological, medical, and business arenas.

Innovative scientific solutions affecting every aspect of the CBMP supply chain, from cultivation to extraction and delivery, are being developed and I felt compelled to contribute to this emerging field. Joining GROW as a start-up organisation was a natural fit for me as their focus on improving patient access to safe, consistent, and reliable medicines aligned with my own. I felt strongly that an organisation like GROW choosing to address the unique challenges that come with a newly-legalised market space would have a lasting and broad-reaching impact.

The scientifically-underwritten approach that GROW has taken toward pharmaceutical supply, clinician empowerment, and underlying scientific understanding of how to access CBMP has been something I am proud to be a part of.”

Investors can talk to me about:

Scientific research, technological innovations, chemical synthesis, collaborations, destigmatizing cannabis, addiction

Notable References

  1. meta-Selective C–H functionalisation of aryl boronic acids directed by a MIDA-derived boronate ester
    Williams, A. F., White, A. J. P., Spivey, A. C., Cordier, C. J.
    Chem. Sci. 2020, 11, 3301–3306
    DOI: https://doi.org/10.1039/D0SC00230E
  2. Rapid Assembly of Saturated Nitrogen Heterocycles in One-Pot: Diazo-Heterocycle “Stitching” by N–H Insertion and Cyclization
    Boddy, A. J., Affron, D. P., Cordier, C. J., River, E. L., Spivey, A. C., Bull, J. A.
    Angew. Chem. Int. Ed. 2019, 58, 5, 1458-1462
    DOI: https://doi.org/10.1002/anie.201812925
  3. Enantioselective propargylic [1,3]-rearrangements: copper-catalyzed O-to-N migrations toward C–N bond formation
    Cheng, L.-J., Brown, A. P. N., Cordier, C. J.
    Chem. Sci. 2017, 8, 4299–4305
    DOI: https://doi.org/10.1039/c7sc01042g
  4. Catalytic Nucleophilic Fluorination of Secondary and Tertiary Propargylic Electrophiles with a Copper–N-Heterocyclic Carbene Complex
    Cheng, L.-J., Cordier, C. J.
    Angew. Chem. Int. Ed. 2015, 54, 46, 13734-13738
    DOI: https://doi.org/10.1002/anie.201506882
  5. Enantioconvergent Cross-Couplings of Racemic Alkylmetal Reagents with Unactivated Secondary Alkyl Electrophiles: Catalytic Asymmetric Negishi α-Alkylations of N-Boc-pyrrolidine
    Cordier, C. J., Lundrgen, R. J., Fu, G. C.
    Am. Chem. Soc. 2013, 135, 30, 10946–10949
    DOI: https://doi.org/10.1021/ja4054114
  6. Catalytic Enantioselective Cross-Couplings of Secondary Alkyl Electrophiles with Secondary Alkylmetal Nucleophiles: Negishi Reactions of Racemic Benzylic Bromides with Achiral Alkylzinc Reagents
    Binder, J. T., Cordier, C. J., Fu, G. C.
    Am. Chem. Soc. 2012, 134, 41, 17003–17006
    DOI: https://doi.org/10.1021/ja308460z
  7. Toward the Total Synthesis of the Brasilinolides: Stereocontrolled Assembly of a C1−C19 Polyol Segment
    Paterson, I, Muhlthau, F. A., Cordier, C. J., Housden, M. P., Burton, P. M., Loiseleur, O.
    Org. Lett. 2009, 11, 2, 353–356
    DOI: https://doi.org/10.1021/ol802562b
  8. Toward the Total Synthesis of the Brasilinolides: Construction of a Differentially Protected C20−C38 Segment
    Paterson, I, Burton, P. M., Cordier, C. J., Muhlthau, F. A., Housden, M. P., Loiseleur, O.
    Org. Lett. 2009, 11, 3, 693–696
    DOI: https://doi.org/10.1021/ol802769e
  9. Toward the Total Synthesis of the Brasilinolides: Construction of a Differentially Protected C20−C38 Segment
    Paterson, I, Burton, P. M., Cordier, C. J., Muhlthau, F. A., Housden, M. P., Loiseleur, O.
    Org. Lett. 2009, 11, 3, 693–696
    DOI: https://doi.org/10.1021/ol802769e
  10. Synthesis of Natural-Product-Like Molecules with Over Eighty Distinct Scaffolds
    Morton, D., Leech, S., Cordier, C. J., Warriner, S., Nelson, A.
    Angew. Chem. Int. Ed. 2008, 48, 1, 104–109
    DOI: https://doi.org/10.1002/anie.200804486

https://www.acexpo.co/london-2019/agenda/speakers/492228

https://podcasts.apple.com/gb/podcast/cannabis-conversation-european-perspective-on-emerging/id1454098889?i=1000433912703

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